CURRICULUM VITAE
Zhongjun Jon Wu, Ph.D.
Professor of Cardiothoracic Surgery
University of Louisville School of Medicine
Date: December 8, 2014
Contact Information
Business Address
Department of Cardiovascular and Thoracic Surgery
Cardiovascular Innovation Institute, room 410
University of Louisville
302 E. Muhammad Ali Blvd
Louisville KY 40202
Phone Number (502) 852 1351
Fax Number (502) 852-5458
E-mail [email protected]
Foreign Languages Chinese
Education
1986 B.S.E. Optical Instruments, Tsinghua University, Beijing, PR China
1989 M.S.E. Optical Engineering, Shanghai Institute of Optics & Fine Mechanics
Chinese Academy of Sciences, PR China
1996 Ph.D. Biomedical Engineering, University of Miami, Coral Gables, FL
Employment History
Academic Appointments:
1996 Research Associate
Department of Biomedical Engineering, University of Miami
1998-2000 Visiting Research Assistant Professor
Department of Surgery, School of Medicine, University of Pittsburgh
2000-2003 Research Assistant Professor
Department of Surgery, School of Medicine, University of Pittsburgh
2003-2009 Assistant Professor
Department of Surgery, University of Maryland School of Medicine
2009- 2011 Associate Professor
Department of Surgery, University of Maryland School of Medicine
2011- 2014 Associate Professor with Tenure
Department of Surgery, University of Maryland School of Medicine
2004-11/2014 Adjunct Faculty Member,
Department of Bioengineering, University of Maryland, College Park, MD
Page 2 Zhongjun Jon Wu, Ph.D.
2014- 11/2014 Professor with Tenure
Department of Surgery, University of Maryland School of Medicine
11/2014- present Professor with Tenure
Department of Cardiovascular and Thoracic Surgery, University of
Louisville School of Medicine
11/2014- present Associate Faculty
Department of Bioengineering, University of Louisville Speed School of
Engineering
Other Employment
1986-1989 Graduate Student Researcher
Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of
Sciences Shanghai, P. R. China
1989-1992 Research Engineer
Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of
Sciences Shanghai, P. R. China
1992-1996 Graduate Student Researcher
Department of Biomedical Engineering, University of Miami, Coral
Gables, FL
1996-1998 Laboratory Project Coordinator/Research Staff
Department of Surgery, UPMC Health System, Pittsburgh, PA
Research Interests and Expertise
Development of Artificial Organs: Ventricular Assist Devices, Blood Pumps, Artificial
Lungs, Respiratory Assist Devices
Computational Modeling and Design Optimization of Blood Contacting Medical Devices
Blood Flow, Flow Visualization, Blood Damage, Cell Mechanics, Cardiac Biomechanics,
Hemodynamics
Biological Responses to Artificial Organs in Human and Animals
Animal Models of Cardiovascular Disease and Development of New Treatment
Technologies
Professional Society Membership
1994-Present Member, American Society for Artificial Internal Organs (ASAIO)
1999-Present Member, Biomedical Engineering Society (BMES)
2002-Present Member, American Society of Mechanical Engineers (ASME)
Honors And Awards 1991 Scientific and Technological Progress Award, Chinese Academy of Sciences 1994 Travel Fellowship Award, American Society for Artificial Internal Organs 1996 Award of Academic Merit, University of Miami
Administrative and Professional Services
Page 3 Zhongjun Jon Wu, Ph.D.
Institutional Services
2003-11/2014 Director, Artificial Organs Laboratory
*Oversee staff of 16 and budget of ~ $2.0 million/year
2009-2010 Alternative Member, School of Medicine Council
11/2014 – present Director of Research, Department of Cardiovascular and Thoracic Surgery,
University of Louisville School of Medicine
Local and National Services
Reviewer for Professional Journals
1999-2014 Regular Reviewer ASAIO Journal (>4/year)
2003-2014 Regular Reviewer Artificial Organs (>3/year)
2003 Acta Biotheoretica
2003 ASME Journal of Fluids Engineering
2005-present Annals of Biomedical Engineering
2006, 2011, 2012 Biomechanics and Modeling in Mechanobiology
2006, 2010 Journal of Biomechanics
2008, 2010, 2012 Journal of Membrane Science
2008, 2010 ASME Journal of Biomechanical Engineering
2008 Applied Physics Letters
2010 Applied Mathematical Modeling
2010-2013 The Open Biomedical Engineering Journal (>1/year)
2010-present Cardiovascular Engineering and Technology (>2/year)
2010-present Journal of Engineering in Medicine (>2/year)
2010 The Open Cardiovascular and Thoracic Surgery Journal
2010 Medical Engineering & Physics (>2/year)
2012 Computers in Biology and Medicine
2011 Biochemical Engineering Journal
2011 Journal of Addiction Research & Therapy
2012 Journal of Biomedical Materials Research: Part A
2012 Stem Cells Translational Medicine
2012 Journal of Healthcare Engineering
2012 Computers in Biology and Medicine
2013 BioMedical Engineering OnLine
2013 Circulation (3)
2013 Journal of Fluids and Structures
2013 Applied Mathematics and Mechanics
2014 Journal of Surgical Research (1)
2014 Mathematical Problems in Engineering (1)
2014 Computers in Biology and Medicine (1)
Reviewer for Books and Book Proposals
1999 University of Pittsburgh patent disclosure
2005 Reviewer, Wiley Encyclopedia of Biomedical Engineering
Page 4 Zhongjun Jon Wu, Ph.D.
2010 Reviewer, Springer Book Proposal
Reviewer for Grants and Research Proposals
2000 Grant Reviewer for USDA Small Business Innovative Research Program
2003 Grant Reviewer for Kentucky Science and Engineering Foundation 2005 Grant Reviewer for Kentucky Science and Engineering Foundation
2006 Grant Reviewer for John Sealy Memorial Endowment Fund for Biomedical Research
2010 Grant Reviewer for Italian Ministry of Health, General Directorate for Health and
Technologies Research,
2013 Grant Reviewer for Italian Ministry of Health, General Directorate for Health and
Technologies Research,
2009 Member of US FDA Technical Review Committee – FY2010 Science Prioritization
Process, Office of Science and Engineering Laboratories, Center for Devices and
Radiological Health, US Food and Drug Administration (FDA) (2009)
2010~2013 Member of NIH Special Emphasis Panel/Scientific Review Study Section
(SBIR/STTR) – Small Business: Cardiovascular and Surgical Devices: ZRG1 SBTS-E
(10) B (Oct. 2010), ZRG1-SBIBV 12 (Feb, 2012), ZRG1-SBIBV12 (June 2012),
ZRG1-SBIB-V12 (March 2013), ZRG1-SBIB-Y12 (June 2013), ZRG1-SBIB-Y12
(Nov.2013)
Reviewer and Organizer for Professional Conferences
2007, 2008, 2013 Reviewer for the ASAIO Annual Conferences
2009 Reviewer for BMES Annual Meeting
2002 Session Chair, International Congress on Biological and Medical Engineering,
Singapore, December, 2002
2007 Session Chair, 53rd ASAIO Annual Conference, - Chicago, IL
2007 Session Chair, 2nd International Joint Congress of the International Federation for
Artificial
2007 Organs (IFAO) and Japanese Society for Artificial Organs (JSAO). Osaka, Japan
October, 2007.
2009 Session Chair, BMES 2009 Annual Conference, October 7 to 10, 2009, Pittsburgh, PA
2010 Associate Chair – Cardiopulmonary Track, ASAIO 2010 Annual Meeting, Baltimore,
MD
2011 Chair – Cardiopulmonary Track, ASAIO 2011 Annual Meeting, Washington DC
2010 Member of Program Committee of ASAIO Annual Meeting
2011 Member of Program Committee of ASAIO Annual Meeting
2014 Member of Program Committee of ASAIO Annual Meeting
2014 Chair – Bioengineering Track, ASAIO 2014 Annual Meeting, Washington DC
Editorial Board
2006-present Member of Editorial Board of ASAIO Journal
2008-present Member of Editorial Board of Open Biomedical Engineering Journal
2013-present Member of Editorial Board of Chronicles of Surgery
2012 Guest Editor, International Journal of Biomaterials – Special Issue on Advanced
Surface Modifications for Blood-Contacting Surfaces of Medical Devices
Page 5 Zhongjun Jon Wu, Ph.D.
External Assessor for Promotion and Tenure
2010 Texas Tech University
2010 University of Michigan
2011 University of Connecticut
2011 University of Louisville
Other Services
2010 Judge, Ph.D. student paper competition at the ASME Summer Bioengineering
Conference
2013 Howard University's Research Day Judging Committee
2011 - 2012 Member of Board of Trustees of the American Society for Artificial Internal
Organs (ASAIO)
Teaching Responsibilities
Student Mentorship and Supervision
University of Pittsburgh:
1998 Alison Curtis, MS, (Senior Engineer, Edwards LifeScience)
1999 Benjamin Ewing, BS, (Engineer Cook Vascular Inc.)
2001 Rebecca K Gottlieb, Ph.D. (Medtronic MiniMed), Research Advisor and PhD Thesis
Committee
2003 Jeffrey Connors, BS, (Material Sciences and Engineering)
2004 Tim Bachman, BS, (MS, University of Pittsburgh, Bioengineering)
2005 Rui Zhao, MS (PhD Student, Carnegie Mellon University)
University of Maryland, Baltimore:
2004 Thesis committee of Rui Zhao’s Master’s Degree (University of Pittsburgh)
2005 Jennifer Lamos (Summer Student, University of Maryland College Park)
2005 Qing Hu (Summer Student, University of Maryland College Park)
2006 Philip Hewes (Summer Student, Biomedical Engineering, University of Michigan)
2006 David Huang (Bioengineering PhD Student Rotation, University of Maryland College
Park)
2007 Julien Azimzadeh (Summer Student, University of Maryland College Park)
2007 Michael J Hickey (Summer Student, VA-MD Regional College of Veterinary Medicine)
2007 Sumair Akhtar (Summer Medical Student, University of Maryland School of Medicine)
2008 Kristina Rotolo (Summer Student, Biomedical Engineering, Duke University)
2008 Charlie Xu (Summer Student, Biomedical Engineering, Duke University)
2008 Adam Pampori (Summer Student, Bioengineering, University of Maryland College
Park)
2008 Ethan Bassett (Summer Medical Student, University of Maryland School of Medicine)
2008 Jeremy Pollock (Summer Medical Student, University of Maryland School of Medicine)
2009 Brian Miller (Summer Medical Student, University of Maryland School of Medicine)
2009 Colin Gause (Summer Medical Student, University of Maryland School of Medicine)
2009 Craig Stauffer (Summer Medical Student, University of Maryland School of Medicine)
2009 Andrea Saltos (Summer Medical Student, University of Maryland School of Medicine)
Page 6 Zhongjun Jon Wu, Ph.D.
2009 Adam Pampori (Summer Student, Bioengineering, University of Maryland College
Park)
2010 Adam Pampori (Summer Student, Bioengineering, University of Maryland College
Park)
2010 Ofra Rybak (Summer Student, Mechanical Engineering, University of Michigan)
2010 Gregory Bittle (Summer Medical Student, University of Maryland School of Medicine)
2010 Bryan Buckingham (Summer Medical Student, University of Maryland School of
Medicine)
2011 Chetan Pasrija (Summer Medical Student, University of Maryland School of Medicine)
2011 Charles R Cooper (Summer Medical Student, University of Maryland School of
Medicine)
2012- present, Jun Ding (PhD Student of Mechanical Engineering, University of Maryland
Baltimore County)
2011-present, Adam Behren (PhD thesis committee member, University of Maryland College
Park)
Post-Doctoral Fellow Mentorship and Supervision
2004 – 2006 Juntao Zhang, PhD
2005 – 2008 Guangming Cheng, MD, PhD
2007 – 2008 Yang Gao, MD
2007 – 2009 Won-Bae Chang, MD
2005 – 2009 Tao Zhang, PhD
2009 – 2010 Giacomo Bianchi, MD
2007 – 2010 M Ertan Taskin, PhD
2008 – 2011 Katharine H Fraser, PhD
2009 – 2011 Kang Zhou, MD
2009 – 2012 Xufeng Wei, MD, PhD
2010 – 2012 Yunshang Zhao, PhD
2010 – 2012 Pei Zhang, PhD
2010 – 2013 Narayana Garimella, PhD
2012 – 2014 Yang Liu, MD, PhD
2009 – 2014 Pablo Sanchez, MD, PhD
2011 – 2014 Jiafeng Zhang, PhD
2102 – present Nandan K Mondal, PhD
2014 – present Zengshen Chen, PhD
Resident Mentorship and Supervision
2004 – 2005 Deyanira Prastein, MD
2004 – 2006 Ahmet Kilic, MD
2005 – 2007 G Kwame Yankey, MD
2008 – 2009 Marc Gibber, MD
2011 – 2013 A Claire Watkins, MD
Page 7 Zhongjun Jon Wu, Ph.D.
Visiting Scholar
2009-2011 Hosting Visiting Associate Professor Ho Sung Son, MD, PhD, Korea
University, College of Medicine. Dept. of Thoracic and Cardiovascular Surgery
Grant Support
Active Grants
07/05/13-03/31/18 (PI: 40%) MPI: BP Griffith/ ZJ Wu
“First-In-Human Use of an Artificial Lung for Ambulatory
Respiratory Support”
NIH/NHLBI 1R01HL118372-01
Total Cost: $4,946,992
Role: PI
06/28/12-06/27/15 (Co-Investigator: 10%) PI: BP Griffith
"Improving MSC Engraftment in the Ischemic Heart"
Maryland Stem Cell Research Fund
Total Cost: $689,958.00
Role: serve as Co-Investigator to manage the daily research
activities for the project
07/24/2013-7/23/2015 (Co-Investigator: 5%) PI: PG Sanchez
“Bone Marrow Derived Stem Cells to Improve Donor Lung
Quality & Transplant Outcomes”
Maryland Stem Cell Research Fund
Total Cost: $200,000
Role: Co-Investigator
01/15/2014 - 12/31/2014 (Co-Investigator: 5%) PI: R Jarvik
“Administrative Center for PumpKIN Pre-Clinical Contractors”
HHSN268201200001I (NIH/NHLBI)
Total Cost: $198,148
Role: Co-Investigator
Pending Grants:
04/1/15-03/31/19 (PI: 20 %) MPI: ZJ Wu/BP Griffith
"Shear-Induced Hemostatic Dysfunction and Bleeding in CF-VAD
recipients"
NIH 1R01 HL124170-01A1
Total Cost: $ 2,119,944 (8 percentile, award is pending)
04/1/15-03/31/19 (PI: 5 %) PI: ZJ Wu (subcontract)
“Paracorporeal VAD for versatile Circulatory Support”
NIH R43HL124830-01A1
Total Cost: $61,400 (Priority Score: 35)
Page 8 Zhongjun Jon Wu, Ph.D.
Completed Grants
05/01/95-09/30/00 (Co-Investigator: 50%) PI: BP Griffith
“Development of the University of Pittsburgh Streamliner Blood
Pump”
McGowan Foundation/University of Pittsburgh
Total Cost: $3,000,000
10/01/95-09/30/00 (Co-Investigator: 25 %) PI: K Butler (Nimbus, Inc.)
“Development of an Innovative Ventricular Assist System”
NIH/NHLB1 N01-HV-58155
Total Cost: $4,091,336 ($2,661,452 contracted to University of
Pittsburgh)
03/01/97-07/01/97 PI
“Flow Visualization Study of AB-180 Centrifugal Blood Pump”
Cardiac Assist Technologies, Inc.
Total Cost: $18,000
08/01/99-12/31/99 PI
“Hemodynamic Study of Arterial Cannulae”
Cardiac Assist Technologies, Inc
Total Cost: $15,000
08/01/99-03/31/00 PI
“Hemodynamic Study of Blood Filtering Devices”
Metamorphic Surgical Devices, Inc.
Total Cost: $13,300
04/01/00-03/31/05 (Co-Investigator: 20%) PI: Bartley P. Griffith
“Bioengineering – Biological Study of Non-Pulsatile Perfusion”
NIH/NIBIB R01EB02076
Total Direct Cost: $1,281,813
07/01/00-05/30/02 (Co-Investigator: 50%) PI: Bartley P. Griffith
“Development of a Chronic Artificial Lung”
NIH/NHLB1 1R01HL60740
Total Direct Cost: $1,993,453
09/01/00-08/31/04 (Co-Investigator:10%) PI: O. Ghattas/JF Antaki
“Simulation of Flows with Dynamic Interfaces on Multi-Teraflop
Computers”
NSF ACI #0086093
Total Cost: $3,113,665
07/01/01-08/31/01 PI
“Flow Visualization Study of Medtronic MiniMed Intravascular
Page 9 Zhongjun Jon Wu, Ph.D.
Glucose Sensor”
Medtronic MiniMed
Total Cost: $2,700
07/01/01-06/30/02 Sub-Contract PI
“Physiological Controller for Rotary Blood Pumps”
NIH/NHLBI-SBIR R43HL066656
Subcontract with Antakamatics Inc
Total Cost: $98,000
07/01/00-05/31/02 (Co-Investigator: 20%) PI: Bartley P. Griffith
“Development of Artificial Organs and Related Products”
State of Pennsylvania
Total Cost: $1,000,000
07/01/01-12/30/02 PI
“Flow Visualization of HeartQuest CF4 Blood Pump”
MedQuest Medical, Inc.
Total Cost: $27,000
10/01/01-03/31/03 (Co-Investigator: 5%) PI: Sarangapani/Antaki
“Fuel Cell Power Packs for Left Ventricular Assist Devices”
NIH/NHLBI 2R44HL61069-02A1
Total Direct Cost: $46,811 (to University of Pittsburgh)
03/01/02-02/28/05 (Co- Investigator: 20%) PI: Michael S. Sacks
“Biomechanical Optimization of TE Heart Valves”
NIH/NHLBI R01HL068816
Total Direct Cost: $750,000
04/01/02-03/31/06 (Co-Investigator/Consultant) PI: William J. Federspiel
“Percutaneous Respiratory Assist Catheter”
NIH/NHLBI R01HL070051
Total Direct Cost: $1,000,000
07/01/02-06/30/03 PI
“Flow Visualization of Thoratec HeartMate III Maglev
Centrifugal Blood Pump”
Engineering and Applied Sciences, Inc.
Total Cost: $13,000
07/01/02-06/30/03 (Co-Investigator: 20%) PI: AJ Russell
“Development of Artificial Organs and Related Products”
Commonwealth of Pennsylvania: ME#02-223
Total Cost: $1,000,000
Page 10 Zhongjun Jon Wu, Ph.D.
07/01/03-06/30/07 Proposal Contributor as Co-Investigator
PI: KB Chandran
“Fluid Structure Simulation for Prosthetic Heart Valves”
NIH/NHLB1 1R01HL071814
Total Direct Cost: $1,139,190
02/01/06-01/31/07 STTR Research Institution PI
PI: B Biancucci/ZJ Wu
“Impeller optimization for a combined pump-oxygenator”
NIH R41 HL083621
Total Cost: $200,046 ($100,309 to University of Maryland)
04/01/06-03/31/07 STTR Research Institution PI
PI: K Dasse/ZJ Wu
“Integrated Maglev Pump-Oxygenator for Respiratory Failure”
NIH R41 HL084807
Total Cost: $266,988 ($101,613 to University of Maryland)
04/01/04-03/31/09 (Co-Investigator: 5 to 30 %) PI: Robert Jarvik/Bartley Griffith
“Pediatric Circulatory Support”
NIH/NHLBI HHSN268200448190C
Total Cost: $5,100,000
06/01/09-08/31/10 PI (supplement support) PI: ZJ Wu
“Linking Multi-scale Dynamics of Shear-Induced Blood Damage
to CFD Modeling”
NIH/NHLBI 3R01HL088100-02S109
Total Cost: $20,625
08/01/09-05/31/12 PI (supplement support) PI: ZJ Wu
“Linking Multi-scale Dynamics of Shear-Induced Blood Damage
to CFD Modeling”
NIH/NHLBI 3R01HL088100-02S209
Total Cost: $204,406
04/01/08-03/31/12 (UMB Principle Investigator: 5 %) PI: K Dasse/ZJ Wu
“Integrated Magley Pump-Oxygenator for Respiratory Failure”
NIH/NHLBI R42 HL084807
Total Cost: $1,395,479 ($732,311 to University of Maryland)
04/01/06-03/31/13 (Co-Investigator: 15 %) PI: Bartley P. Griffith
“Strain Controlled LVAD Unloading and Post MI Remodeling”
NIH/NHLBI R01 HL 081106
Total Cost: $3,541,678
Page 11 Zhongjun Jon Wu, Ph.D.
Role: serve as Co-Investigator to manage the daily research
activities for the project
05/01/09-04/30/13 (Co-Investigator: 5%) PI: Bartley P Griffith
“Engineering Cardiac Stem Cells for Heart Repair”
McGowan Charitable Fund
Total Cost: $330,000
Role: serve as Co-Investigator to manage the daily research
activities for the project
07/15/09 - 7/31/13 (UMB PI: 5%) PIs: G Farnan/ZJ Wu
“CircuLite's Circulatory Support System in Children and Infants”
NIH/NHLBI 1R44HL096214 (NCE)
Total Cost: $2,943,568.80
01/15/10-01/14/14 (Co-Investigator: 10 %) PI: BP Griffith
“Pumps for Kids, Infants and Neonates (PumpKIN) Pre-Clinical
Program”
NIH/NHLBI HHSN268201000014C
Total Cost: $5,428,839
Role: serve as Co-Investigator to manage the daily activities for the
project
01/15/10-01/14/14 (Co-Investigator: 10 %) PIs: R Jarvik/BP Griffith
“Pumps for Kids, Infants and Neonates (PumpKIN) Pre-Clinical
Program”
NIH/NHLBI HHSN268201000013C
Total Cost: $6,853,583
Role: serve as Co-Investigator to manage the daily research
activities for the project
08/1/12-07/31/14 (Co-PI: 2%) PIs: P Kofinas/ZJ Wu
"Synthetic Polymer Functional Hydrogel for Hemorrhage Control"
University of Maryland Baltimore-University of Maryland College
Park Seed Grant
Total Cost: $75,000
07/24/13-7/23/15 (Co-Investigator, 5%) PI: PG Sanchez
"Bone Marrow Derived Stem Cells to Improve Donor Lung
Quality & Transplant Outcomes"
Maryland Stem Cell Research Fund
Total Cost: $200,000
05/1/2013-04/30/15 (PI: 1%) PI: ZJ Wu
"Particle Image Velocimetry (PIV) Study of the Thoratec
HeartMate III Ventricular Assist Device"
Page 12 Zhongjun Jon Wu, Ph.D.
Thoratec Corporation
Total Cost: $50,000
05/01/07-04/30/14 (Co-Investigator: 15 %) PI: BP Griffith
“Development of an Artificial Pump-Lung for Respiratory
Failure”
NIH/NHLBI R01 HL082631
Total Cost: $3,575,860
Role: serve as Co-Investigator to manage the daily research
activities for the project
09/01/08-05/31/14 (PI: 15 %) PI: ZJ Wu
“Linking Multi-scale Dynamics of Shear-Induced Blood Damage
to CFD Modeling”
NIH/NHLBI R01 HL 088100
Total Cost: $1,461,500
Patents
1. Touch down of blood pump impellers. US Patent 6,761,532, July 13, 2004.
2. Method and apparatus for providing limited back-flow in a blood pump during a non-
pumping state. US patent application filed on December 19, 2002. US Patent Application
Publication No.: US 2003/0144574 A1. July 31, 2003.
3. Blood Pump-Oxygenator System. US patent application filed on September 13, 2004. US
Patent Application Publication No.: US 2007/0249888 A1. October 25, 2007.
4. Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a
method of a method of de-bubbling and priming an extracorporeal life support system. US
Patent 8,496,874 B2, August 2013.
5. Biocompatible Coating Compositions. US Patent Application PCT/US2014/010391, filed on
January 7, 2014.
6. Self-Expanding Cannula. US Patent Application PCT/US14/46978, file on July 18, 2014.
7. Blood Oxygenator. US Provisional Patent Application, filed on December 22, 2013.
8. Self-Seal Double Lumen Cannula. US Provisional Patent Application filed on November 14,
2014.
9. An Artificial Lung System and Its Methods of Use. US Provisional Patent Application filed
on November 19, 2014.
Publications
Peer-reviewed Journal Articles
1. Yang XY, Wu ZJ and Wu MX. A New Optical Method Used for Measuring the Runout of
Shafting. Measurement Technique, No. 2: 1-3, 1988, (in Chinese).
Page 13 Zhongjun Jon Wu, Ph.D.
2. Chen QS and Wu ZJ. A Simple Measurement Method of Repeatability Error of Limit Switch.
Measurement Technique, No. 12: 14-15, 1990 (in Chinese).
3. Wu ZJ, Chen XZ and Sun BD. A Vibrating Stage with Spring-supporting for Testing
Recording Characteristics of Optical Storage Media. Chinese Journal of Lasers, 18:333-336,
1991 (in Chinese).
4. Li XS, Wu ZJ, Gan BH and Sun JF. An Automatic Instrument for Measuring Defects of
Optical Disk Substrates. Chinese Journal of Scientific Instrument. Vol.13: 136-142, 1992 (in
Chinese).
5. Wu ZJ, Li XS, Gan BH and Sun JF. Fast Classification and Counting of Surface Defects and
Evaluation of Surface Performances for Optical Disks. Chinese Journal of Lasers, Vol. A20,
No. 12: 921-925, 1993.
6. Bluestein D, Menon S, Wu ZJ, Haubold A, Armitage TH and Hwang NH. Closing Behavior
of a New Bileaflet Mechanical Heart Valve. ASAIO J 39:398-402, 1993.
7. Wu ZJ, Shu MC, Scott DR and Hwang NH. The Closing behavior of Medtronic Hall
Mechanical Heart Valves. ASAIO J 40: 702-706, 1994.
8. Wu ZJ, Wang Y and Hwang NH. Occluder Closing Behavior: A key Factor in Mechanical
Heart Valve Cavitation. J Heart Valve Dis 3 (Suppl. I): 25-34, 1994.
9. Wu ZJ, Gao BZ and Hwang NH. Transient Pressure at Closing of a Monoleaflet Mechanical
Heart Valve Prosthesis: Mounting Compliance Effect. J Heart Valve Dis 4:553-567, 1995.
10. Wu ZJ and Hwang NH. Ventricular Pressure Slope (dp/dt) and Bileaflet Mechanical Heart
Valve Closure. ASAIO J 41:763-767, 1995.
11. Wu ZJ and Hwang NH. Asynchronous Closure and Leaflet Impact Velocity of Bileaflet
Mechanical Heart Valves. J Heart Valve Dis 4: (Suppl. I): 38-49, 1995.
12. Wu ZJ, Slonin JH and Hwang NH. Transient Pressure Signals in Mechanical Heart Valve
Cavitation. ASAIO J 42: 555-561, 1996.
13. Wu ZJ, Gao BZ, Slonin JH and Hwang NH. Bileaflet Mechanical Heart Valves at Low
Cardiac Outputs. ASAIO J 42: 747-749, 1996.
14. Amin DV, Antaki JF, P Litwak, Thomas D, Wu ZJ, Yu YC, Choi S, Boston JR and Griffith
BP. Controller for an Axial Flow Blood Pump. Biomed Instrum Technol 31:483-487, 1997.
15. Thomas DC, Butler KC, Taylor LP, Le Blanc P, Griffith BP, Kormos RL, Borovetz HS, Wu
ZJ and Antaki JF. Continued Development of the Nimbus/University of Pittsburgh (UOP)
Axial Flow Left Ventricular Assist System. ASAIO J 43:564-566, 1997
16. Amin DV, Antaki JF, Litwak P, Thomas D, Wu ZJ, Watach M. Induction of ventricular
collapse by an axial flow blood pump. ASAIO J 44: M685-690, 1998.
17. Curtis AS, Wu ZJ, Kormos RL and Antaki JF.A Novel Ventricular Apical Cannula: In-Vitro
Evaluation Using Transparent Compliant Casts. ASAIO J 44: 691-695, 1998.
18. Thomas D, Butler KC, Taylor L, LeBlanc P, Griffith B, Kormos R, Borovetz H, Litwak P,
Kameneva M, Choi S, Burgreen G, Wu Z, Antaki J. Year two progress of the Nimbus-
University of Pittsburgh (UoP) axial flow left ventricular assist system. ASAIO J 44: M521-
524, 1998.
Page 14 Zhongjun Jon Wu, Ph.D.
19. Wu ZJ, Antaki JF, Burgreen GW, Thomas D, Butler KC and Griffith BP. Fluid Dynamic
Characterization of Operating Conditions for Continuous Flow Blood Pumps. ASAIO J 45:
442-449, 1999.
20. Burgreen GW, Antaki JF, Wu ZJ, LeBlanc P and Butler KC. A Computational and
Experimental Comparison of Two outlet Stators for the Nimbus LVAD. ASAIO J 45:328-
333, 1999.
21. Wu ZJ, Gottlieb RK, Burgreen GW, Holmes JA Borzelleca DC, Kameneva MV Griffith
BP, and Antaki JF. Investigation of Fluid Dynamics within a Miniature Mixed Flow Blood
Pump. Experiments in Fluids 31:615-629, 2001.
22. Burgreen GW, Antaki JF, Wu ZJ, Holmes JA. Computational fluid dynamics as a
development tool for rotary blood pumps. Artificial Organs 25:336-340, 2001.
23. Litwak KN, Kihara S, Kameneva MV, Litwak P, Uryash A, Wu ZJ, Griffith BP. Effects of
continuous flow left ventricular assist device support on skin tissue microcirculation and
aortic hemodynamics. ASAIO Journal 49:103-107, 2003.
24. Kihara S, Litwak KN, Nichols L, Litwak P, Kameneva MV, Wu ZJ, Kormos RL, Griffith
BP. Smooth muscle cell hypertrophy of renal cortex arteries with chronic continuous flow
left ventricular assist. Annals of Thoracic Surgery 75: 178-83, 2003.
25. Hildebrand D, Wu ZJ, Mayer J, Sacks M. Design and Hydrodynamic Evaluation of A Novel
Pulsatile Bioreactor for Biologically Active Heart Valves. Annals of Biomedical Engineering
32(8):1039-1049, 2004.
26. Kameneva MV, Wu ZJ, Urash A, Repko B, Litwak KN, Billiar TR, Fink MP, Simmons RL,
Griffith BP, Borovetz HS. Blood soluble drag-reducing polymers prevent lethality from
hemorrhagic shock in acute animal experiments. Biorheology 41(1):53-64, 2004.
27. Burgreen GW, Loree HW, Bourque K, Dague C, Poirier VL, Farrar D, Hampton E, Wu ZJ,
Gempp TM, Schöb R. Computational Fluid Dynamics Analysis of a Maglev Centrifugal Left
Ventricular Assist Device. Artificial Organs 28: 874-881, 2004.
28. Litwak KN, Koenig SC, Tsukui H, Kihara S, Wu Z, Pantalos GM. Effects of left ventricular
assist device support and outflow graft location upon aortic blood flow. ASAIO J 50:432-7,
2004.
29. Wu ZJ, Gartner M, Litwak KN, Griffith BP. Progress toward an ambulatory artificial lung. J
Thorac Cardiovasc Surg. 2005 Oct; 130(4):973-8.
30. Zhao R, Antaki JF, Naik T, Bachman TN, Kameneva MV, Wu ZJ. Microscopic
Investigation of Erythrocyte Deformation Dynamics. Biorheology 2006, Vol. 43: 747 - 765.
31. Kilic A, Li T, Nolan TDC, Nash JR, Li S, Prastein DJ, Schwartzbauer G, Moainie SL,
Yankey GK, DeFilippi C, Wu ZJ and Griffith BP. Strain-Related Regional Alterations of
Calcium-Handling Proteins in Myocardial Remodeling. J Thorac Cardiovasc Surg,
132(4):900-8, 2006.
32. Zhang J, Gellman B, Koert A, Dasse KA, Gilbert RJ, Griffith BP, Wu ZJ. Computational
and Experimental Evaluation of the CentriMag® Blood Pump. Artificial Organs 30 (3):168-
177, 2006.
33. Gammie JS, Yankey GK, Nolan T, Wu ZJ, Dickfeld T, Cartier C, Tremblay A; MacNeil TP,
Burke A, Griffith BP. Beating Heart Direct Left Atrial Access Balloon Cryoablation: Safety
Page 15 Zhongjun Jon Wu, Ph.D.
and Efficacy of Pulmonary Vein Isolation in an Ovine Model. Innovations: Technology &
Techniques in Cardiothoracic & Vascular Surgery. 2(4):188-191, July 2007
34. Kilic A, Nolan TDC, Li T, Yankey GK, Prastein DJ, Jarvik RK, Wu ZJ and Griffith BP.
Early In-Vivo Experience with the Pediatric Jarvik 2000 Heart. ASAIO Journal 53 (3):374-8,
2007 (corresponding author).
35. Zhang J, Koert A, Gellman B, Gempp T, Dasse KA, Gilbert RJ, Griffith BP and Wu ZJ.
Optimization of a Miniature Maglev Ventricular-Assist Device (VAD) for Pediatric
Circulatory Support. ASAIO J. 53(1):23-31, 2007.
36. Zhang J, Nolan TDC, Zhang T, Griffith BP and Wu ZJ. Characterization of membrane blood
oxygenation devices using computational fluid dynamics. Journal of Membrane Science. Vol.
288(1-2): 268-279, 2007
37. Yankey GK, Li T, Kilic A, Cheng G, Satpute A, Savai K, Li S, Moainie SL, Prastein D,
DeFillipi C, Wu ZJ, Griffith BP. Regional Remodeling Strain and Its Association with
Myocardial Apoptosis Post-Myocardial Infarction in Ovine Model. J Thorac Cardiovasc Surg
135(5):991-8, 998.e1-2, 2008.
38. Gottlieb RK, Shu F, Kameneva MV, Antaki JF, Wu ZJ, Burgreen GW. Liquid crystal shear
stress sensor for blood and other opaque viscous fluids. Journal of Flow Visualization and
Image Processing. 16: 51-71, 2009.
39. Zhang T, Cheng G, Koert A, Zhang J, Gellman B, Yankey GK, Satpute A, Dasse KA, Gilbert
RJ, Griffith BP, Wu ZJ. Functional and Biocompatibility Performances of an Integrated
Maglev Pump-Oxygenator. Artificial Organs 33 (1):36-45, 2009.
40. Zhang J, Taskin ME, Koert A, Zhang T, Gellman B, Dasse KA, Gilbert RJ, Griffith BP, Wu
ZJ. Computational Design and In-Vitro Characterization of an Integrated Maglev Pump-
Oxygenator (IMPO). Artificial Organs 2009; 33:805-817.
41. Marhefka JN, Zhao R, Wu ZJ, Velankar SS, Antaki JF and Kameneva MV. Drag reducing
polymers improve tissue perfusion via modification of the RBC traffic in microvessels.
Biorheology 2009; 46:281-292.
42. Pantalos G, et al. Use of computer and in vitro modeling techniques during the development
of pediatric circulatory support devices: National Heart, Lung, and Blood Institute Pediatric
Assist Device Contractor's Meeting: Pediatric Modeling Techniques Working Group. ASAIO
J. 2009; 55:3-5. Erratum in: ASAIO J. 2009;55:307.
43. Fraser KH, Zhang T, ME Taskin, Griffith BP, Wu ZJ. Computational Fluid Dynamics
Analysis of Thrombosis Potential in Left Ventricular Assist Device Drainage Cannulae.
ASAIO Journal 56:157-163, 2010.
44. Gibber M, Wu ZJ, Chang WB, Bianchi G, Hu J, Garcia J, Jarvik R, Griffith BP. In-Vivo
Experience of the Child Size Pediatric Jarvik 2000 Heart: Update. ASAIO J. 2010 Jul-
Aug;56(4):369-76. PMID: 20467298 (corresponding author).
45. Taskin ME, Zhang T, Gellman B, Fleischli A, Dasse KA, Griffith BP, Wu ZJ.
Computational Characterization of Flow and Hemolytic Performance of the UltraMag TM
Blood Pump for Circulatory Support. Artificial Organs 2010 Dec;34(12):1099-113.. PMID:
20626739.
Page 16 Zhongjun Jon Wu, Ph.D.
46. Taskin ME, Fraser KH, Zhang T, Griffith BP, Wu ZJ. Micro-scale Modeling of Flow and
Oxygen Transfer in Hollow Fiber Membrane Bundle. Journal of Membrane Science 2010;
362: 172-183. PMID: 20802783.
47. Casey BJ, Behrens AM, Hess JR, Wu ZJ, Griffith BP, Kofinas P. FVII Dependent
Coagulation Activation in Citrated Plasma by Polymer Hydrogels. Biomacromolecules. 2010
Dec 13;11(12):3248-55. PMID: 21058718.
48. Fraser KH, Taskin ME, Griffith BP, Wu ZJ. The use of Computational Fluid Dynamics in
the Development of Mechanical Circulatory Support Devices. Med Eng Phys. 2011
Apr;33(3):263-80. PMID: 21075669.
49. Zhang T, Taskin ET, Fang HB, Pampori A, Jarvik R, Griffith BP, Wu ZJ. Study of Flow-
induced Hemolysis using Novel Couette-Type Blood-Shearing Devices. Artificial Organs
2011 Dec;35(12):1180-6.
50. Garcia JP, Kon ZN, MD, Evans C, Wu Z, Iacono AT, McCormick B and Griffith BP.
Ambulatory veno-venous extracorporeal membrane oxygenation: Innovation and pitfalls. J
Thorac Cardiovasc Surg. 2011 Oct;142(4):755-61. PMID: 21924145
51. Wu ZJ, Gellman B, Zhang T, Taskin ME, Dasse KA, Griffith BP. Computational Fluid
Dynamics and Experimental Characterization of the Pediatric Pump-Lung. Cardiovasc Eng
Tech 2011; 2:276-287.
52. Zhang T, Wei X, Bianchi G, Griffith BP and Wu ZJ. A novel wearable pump-lung device:
in-vitro and acute in-vivo study. Journal of Heart and Lung Transplantation, 2012
Jan;31(1):101-5. Epub 2011 Oct 20. PMID: 22014451 (Featured on cover page).
53. Wu ZJ, Zhang T, Bianchi G, Wei X, Son H-S, Zhou K, Taskin ME, Wang P, Bianccuci B,
Garcia J, Griffith BP. 30-Day In-vivo Performance of a Wearable Artificial Pump-Lung for
Ambulatory Respiratory Support. Ann Thorac Surg. 2012 Jan;93(1):274-81.
54. Wu ZJ, Taskin ME, Zhang T, Griffith BP. Computational Model-Based Design of a
Paracorporeal Artificial Pump-Lung for Cardiopulmonary/Respiratory Support. Artif Organs.
2012 Apr;36(4):387-99. doi: 10.1111/j.1525-1594.2011.01369.x. [Epub ahead of print]
PMID: 22145732.
55. Taskin ME, Fraser KH, Zhang T, Wu CF, Griffith BP, Wu ZJ. Evaluation of Eulerian and
Lagrangian Models for Hemolysis Estimation. ASAIO J. 2012 Jul;58(4):363-72. PMID:
22635012
56. Taskin ME, Zhang T, Fraser KH, Griffith BP, Wu ZJ. Design Optimization of a Wearable
Artificial Pump-Lung Device with Computational Modeling. ASME Journal of Medical
Devices 2012, Vol. 6 / 031009-1. [DOI: 10.1115/1.4007282]
57. Fraser KH, Zhang T, Taskin ME, Griffith BP, Wu ZJ. A Quantitative Comparison of
Mechanical Blood Damage Related Parameters in Rotary Ventricular Assist Devices. ASME
Journal of Biomechanical Engineering 2012, Vol. 134 / 081002-1. [DOI:10.1115/1.4007092]
58. Wu ZJ, Garimella N, Larsson R, Brynda E. Advanced Surface Modifications for Blood-
Contacting Surfaces of Medical Devices. Int J Biomater. 2012; 2012:291735. doi:
10.1155/2012/291735. Epub 2012 Jul 5.PMID: 22829827.
59. Zhao Y, Li T, Wei X, Bianchi G, Hu J, Sanchez PG, Xu K, Zhang P, Pittenger MF, Wu ZJ,
Griffith BP. Mesenchymal Stem Cell Transplantation Improves Regional Cardiac Remodeling
Page 17 Zhongjun Jon Wu, Ph.D.
Following Ovine Infarction. Stem Cells Translational Medicine 2012;1:685– 695 (co-
corresponding author, featured paper with press release).
60. Sanchez PG, Bittle GJ, Williams K, Pasrija C, Xu K, Wei X, Garcia JP, Wu ZJ, Griffith BP.
Ex-Vivo Lung Evaluation Of Pre-Arrest Heparinization in Donation After Cardiac Death.
Annals of Surgery 2013 Mar;257(3):534-41. doi: 10.1097/SLA.0b013e318273bef1.PMID:
23108122.
61. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. Chronic Animal models for evaluation of
implantable pediatric ventricular assist devices. ASAIO J. 2013 Jan-Feb;59(1):75-80. doi:
10.1097/MAT.0b013e31827986fe. Erratum in: ASAIO J. 2013 Mar-Apr;59(2):193. Sanchez,
Pablo [corrected to Sanchez, Pablo G]. PMID:23254234 (corresponding author)
62. Wei X, Li T, Li S, Son HS, Sanchez PG, Niu S, Watkins AC, DeFilippi C, Jarvik R, Wu ZJ,
Griffith BP. Acute hemodynamic evaluation of the infant Jarvik ventricular assist device in a
piglet animal model. Journal of Heart and Lung Transplantation 2013 Jan;32(1):112-9. doi:
10.1016/j.healun.2012.10.011.PMID: 23260711(Corresponding author) (Featured on cover
page).
63. Zhang J, Zhang P, Fraser KH, Griffith BP, Wu ZJ. Comparison of fluid dynamic numerical
models for a clinical ventricular assist device and experimental validation. Artificial Organs
2013 Apr;37 (4):380-9. doi: 10.1111/j.1525-1594.2012.01576.x. Epub 2013 Feb 27.PMID:
23441681.
64. Zhou K, Niu S, Bianchi G, Wei X, Garimella N, Griffith BP, Wu ZJ. Biocompatibility
Assessment of a Long-Term Wearable Artificial Pump-Lung in Sheep. Artif Organs. 2013
Aug;37(8):678-88. doi: 10.1111/aor.12049. Epub 2013 Mar 3.PMID: 23452221.
65. Wei X, Li T, Hagen B, Zhang P, Sanchez P, Williams K, Li S, Bianchi G, Son HS, Wu C,
DeFilippi C, Xu KY, Lederer WJ, Wu ZJ, Griffith BP. Short-term Mechanical Unloading
with Left Ventricular Assist Devices after Acute Myocardial Infarction Conserves Calcium
Cycling and Improves Heart Function. JACC: Cardiovascular Interventions 2013
Apr;6(4):406-15. doi: 10.1016/j.jcin.2012.12.122. Epub 2013 Mar 20.PMID: 23523452 (co-
corresponding author).
66. Li T, Kilic A, Wei X, Wu C, Schwartzbauer G, Yankey K, DeFilippi C, Bond M, Wu ZJ,
Griffith BP. Regional imbalanced activation of the calcineurin/BAD apoptotic pathway and
the PI3K/Akt survival pathway after myocardial infarction. Int J Cardiol. 2013 Jun
5;166(1):158-65. doi: 10.1016/j.ijcard.2011.10.107. Epub 2011 Nov 15. [Epub ahead of print]
PMID: 22088220 (co-corresponding author).
67. Li T, Wei X, Sanchez PG, AC Watkins, Wu ZJ, Griffith BP. Prophylactic amiodarone and
lidocaine improve survival in an ovine model of large size myocardial infarction. J Surg Res.
2013 Nov;185(1):152-8. doi: 10.1016/j.jss.2013.05.050. Epub 2013 Jun 7. PMID:23773712
(co-corresponding author).
68. Mondal NK, Sorensen E, Hiivala N, Feller E, Griffith BP, and Wu ZJ. Oxidative Stress,
DNA Damage and Repair in Heart Failure Patients after Implantation of Continuous Flow
Left Ventricular Assist Devices. Int J Med Sci. 2013 May 20;10(7):883-93. doi:
10.7150/ijms.6219. Print 2013. PMID: 23781134.
69. Casey BJ, Behrens AM, Tsinas ZI, Hess JR, Wu ZJ, Griffith BP, Kofinas P. In vitro and in
vivo evaluation of polymer hydrogels for hemorrhage control. J Biomater Sci Polym Ed
Page 18 Zhongjun Jon Wu, Ph.D.
2013;24(15):1781-93. doi: 10.1080/09205063.2013.801707. Epub 2013 Jun 6.
70. Gao Y, Li T, Wu C, Bittle G, Chen S, Wu ZJ, Griffith BP. Pim-1 Mediated Signaling during
the Process of Cardiac Remodeling Following Myocardial Infarction in Ovine Hearts. J Mol
Cell Cardiol. 2013 Oct;63:89-97. doi: 10.1016/j.yjmcc.2013.07.012. Epub 2013 Jul 27.
PMID: 23899906 (co-corresponding author).
71. Zhang JF, Chen X, Fraser KH, Taskin ET, Griffith BP, Wu ZJ. Computational Study of the
Blood Flow in Three Types of 3D Hollow-Fiber Membrane Bundles. J Biomech Eng. 2013
Dec;135(12):121009. doi: 10.1115/1.4025717. PMID: 24141394
72. Hu J, Mondal NK, Sorensen E, Cai L, Fang HB, Griffith BP, Wu ZJ. Platelet glycoprotein
Ibα (GPIbα) ectodomain shedding and non-surgical bleeding in heart failure patients
supported by continuous flow left ventricular assist devices (CF-LVADs). J Heart Lung
Transplant. 2014 Jan;33(1):71-9. doi: 10.1016/j.healun.2013.08.013. Epub 2013 Sep
19.PMID: 24055626
73. Behrens AM, Sikorski MJ, Li T, Wu ZJ, Griffith BP, Kofinas P. Blood Aggregating
Hydrogel Particles for Use as a Hemostatic Agent. Acta Biomater. 2014 Feb;10(2):701-8.
PMID: 24185001
74. Liu Y, Sanchez PG, Wei X, Li T, Watkins AC, Li SY, Griffith BP, Wu ZJ. Right ventricular
unloading and respiratory support with a wearable artificial pump-lung (APL) in an ovine
model. J Heart Lung Transplant. 2014 Feb 26. pii: S1053-2498(14)01004-3. doi:
10.1016/j.healun.2014.02.026. [Epub ahead of print]. PMID:24746636
75. Mondal NK, Sorensen EN, Hiivala NH, Feller ED, Pham SM, Griffith BP, Wu ZJ.
Intraplatelet reactive oxygen species, mitochondrial damage and platelet apoptosis augment
non-surgical bleeding in heart failure patients supported by continuous-flow left ventricular
assist device. Platelets. 2014 Aug 28:1-9. [Epub ahead of print] PMID: 25167344
76. Zhao Y, Hu J, Buckingham B, Pittenger M, Wu ZJ, Griffith BP. Pim-1 kinase cooperates
with serum signal supporting MSC propagation. Cells Tissues Organs. 2014 Nov 11. [Epub
ahead of print]. PMID:25402318 (corresponding author).
77. Ding J, Chen Z, NiuS, Zhang J, Mondal NK, Griffith BP and Wu ZJ. Quantification of
Shear-Induced Platelet Activation: High Shear Stresses for Short Exposure Time. Artif
Organs (in press).
78. Wei X, Sanchez PG, Liu Y, Li T, Watkins AC, Wu ZJ, Griffith BP. Mechanical Circulatory
Support of a Univentricular Fontan Circulation with a Continuous Axial-Flow Pump in a
Piglet Model. ASAIO J. 2014 Nov 13. [Epub ahead of print] PMID: 25396272
(corresponding author).
79. Ding J, Niu S, Chen Z, Zhang T, Griffith BP, Wu ZJ. Shear-Induced Hemolysis: Species
Differences. Artif Organs (in press).
80. Liu Y, Sanchez PG, Wei X, Watkins AC, Niu S, Wu ZJ, Griffith BP. Thirty-Day
Cardiopulmonary Support with a Novel Pediatric Pump-Lung (PediPL) in an Ovine Animal
Model. Artif Organs (accepted, minor revision) (corresponding author).
Book Chapters:
Page 19 Zhongjun Jon Wu, Ph.D.
1. Wu ZJ, JF Antaki, K Litwak, MV Kameneva, HS Borovetz, RL Kormos. Ventricular assist
devices: current status and future perspective. In New Frontiers in Biomedical Engineering.
Hwang (ed), Kluwer Academic Publisher, New York, 2003.
Peer Reviewed Conference Papers
1. Yan HB, Gan FX and Wu ZJ. Structural Change Characteristics of the Vapor-deposited
Al-Cu Alloy Films. SPIE, Vol. 1230: 699-700, 1990.
2. Wu ZJ, Pan T, Chen XZ, Sun BD and Yuan HJ. Investigation of the Microscopical
Readout Characteristics of Optical Recording Media. SPIE, Vol. 1230: 675-677, 1990.
3. Curtis AS, Meyer RK, Wu ZJ, Burgreen GW, Antaki JF. Application of bioluminescent
plankton for shear stress measurement within circulatory assist components. Proc Int Conf
on Cardiac Mechanics in Medicine and Biology, Hawaii, 1998.
4. Wu ZJ, Burgreen GW, Thomas D, Butler KC, Griffith BP and Antaki JF. Visualization of
Flow Features in a Miniature Axial Flow Blood Pump Using Laser-Based Fluorescent Particle
Imaging Technique. Proceedings of the 8th International Symposium on Flow Visualization,
paper 112, Italy, September 1998.
5. Gottlieb RK, Wu ZJ, Borovetz HS and Antaki JF. Calibration of a Novel Liquid Crystal
Shear Stress Sensor. Proceedings of the 8th International Symposium on Flow Visualization,
paper 113, Italy, September 1998.
6. Wu ZJ, Sturk K, Marascalco P, Marhefka, J Kameneva MV. Modification of Flow Behavior
of Red Blood Cells by Blood Soluble Drag-Reducing Polymers. Proceedings of International
Congress on Biological and Medical Engineering, Singapore, December, 2002.
7. Marascalco PJ, Pensenstadler KL, Smith GC, Baer SA, JN Marhefka, Wu ZJ, Kameneva
KV. Effect of drag reducing polymers (DRPs) on red blood cell (RBC) filterability.
Biomedical Engineering: Recent Developments. J Vossoughi (editor), 2002
8. Antaki JF, Boston JR, Simaan M, and Wu Z. Current strategies for control of turbodynamic
blood pumps. Proceedings of 2nd Joint Conference of the IEEE Engineering in Medicine and
Biology Society and the Biomedical Engineering Society, Houston, October, 2002.
9. Zhang J, Nolan TDC, Griffith BP, and Wu ZJ. Computational and In-vitro Characterization
of Pressure Drop and Oxygenation in Blood Membrane Oxygenators. Proceedings of the
American Society of Mechanical Engineers Summer Bioengineering Conference, June 22-26,
2005.
10. Zhang J, Nolan TDC, Egerton M., Griffith BP, and Wu ZJ. Numerical Prediction of Shear
Stress Induced Hemolysis in Biomedical Devices. Proceedings of the American Society of
Mechanical Engineers Summer Bioengineering Conference, June 22-26, 2005.
11. Wu ZJ, Prastein D, Kilic A, Moainie S, Egerton M, Nash JR, Sacks MS, and Griffith
BP. Strain Mapping of LVAD Unloading and Post MI Remodeling. Proceedings of the
American Society of Mechanical Engineers Summer Bioengineering Conference, June 22-26,
2005.
12. Taskin ME, Zhang T, Wu C, Griffith BP, Wu ZJ, "CFD Assisted Design of a Wearable
Artificial Pump Lung Device", Proceedings of ASME International Mechanical Engineering
Congress & Exposition, Boston, MA. Oct. 31-Nov. 6, 2008.
13. Wu C, Li T, Savai K, Griffith BP, Wu ZJ. Strain mapping of LV myocardium and its
correlation with activation of apoptotic molecular pathways post infarction. Presented at the
Page 20 Zhongjun Jon Wu, Ph.D.
ASME 2008 Summer Bioengineering Conference (SBC2008). Marriott Resort, Marco Island,
Florida, USA, June 25-29, 2008.
14. Taskin ME, Zhang T, Gellman B, Dasse KA, Griffith BP, and Wu ZJ. 3D flow modeling
and blood damage characterization of the ultramag™ blood pump. Presented at the ASME
2008 Summer Bioengineering Conference (SBC2008). Marriott Resort, Marco Island,
Florida, USA, June 25-29, 2008.
15. Taskin EM, Zhang T, Griffith BP, and Wu ZJ. Computational Analysis of a Wearable
Artificial Pump Lung Device in Terms of Rotor/Stator Interactions. The ASME 2009
Summer Bioengineering Conference, June 17 to 21, 2009, Lake Tahoe, CA.
16. Wu C, Chang WB, Gibber M, Griffith BP, Wu ZJ. Bioengineering Quantification of Left
Ventricular Remodeling Following Myocardial Infarction. The ASME 2009 Summer
Bioengineering Conference, June 17 to 21, 2009, Lake Tahoe, CA.
17. Fraser KH, Taskin ME, Zhang T, RRichardson S, Gellman B, Dasse B, Griffith BP, Wu ZJ.
The effect of impeller position on CFD calculations of blood flow in magnetically levitated
centrifugal blood pumps. Proceedings of the American Society of Mechanical Engineers
Summer Bioengineering Conference (SBC2010). June 16-19, Grande Beach Resort, Naples,
Florida, USA.
18. Taskin ME, Zhang T, Griffith BP, and Wu ZJ. Design Optimization of a Wearable Artificial
Pump-Lung Device with Computational Modeling. Proceedings of the American Society of
Mechanical Engineers Summer Bioengineering Conference (SBC2010). June 16-19, Grande
Beach Resort, Naples Florida, USA.
19. Engel E, Wu ZJ, and Griffith BP. Early Remodeling Strain Levels Can Predict The
Progression of Remodeling of The Left Ventricle Post Myocardial Infarction. Proceedings of
the American Society of Mechanical Engineers Summer Bioengineering Conference
(SBC2010). June 16-19, Grande Beach Resort, Naples, Florida, USA.
20. K H Fraser, M E Taskin, T Zhang, B P Griffith and Z J Wu Comparison of Shear Stress,
Residence Time and Lagrangian Estimates of Hemolysis in Different Ventricular Assist
Devices. 26th Southern Biomedical Engineering Conference, 2010, IFMBE Proceedings, 32,
pp 548-551
21. Zhang P, Li T, Williams K, Li S, Wei X, Son H, Sanchez P, Griffith BP, Wu ZJ. Analysis of
Mechanical Effects on Myocardial Infarction Remodeling. Proceedings of the ASME 2011
Summer Bioengineering Conference, June 22-25, 2011, Farmington, PA.
22. Fraser KH, Zhang T, Griffith BP, Wu ZJ. Differences in Shear Stress, Residence Time and
Estimates Of Hemolysis between Different Ventricular Assist Devices. Proceedings of the
ASME 2011 Summer Bioengineering Conference, June 22-25, 2011, Farmington, PA.
23. Zhang J, Zhang P, Fraser K, Griffith BP, Wu ZJ. Experimental Validation of Fluid Dynamic
Numerical Models in Blood Pump Simulation. Proceedings of the ASME 2012 Summer
Bioengineering Conference, (SBC2012), June 20-23, Fajardo, Puerto Rico, USA.
Published Abstracts and Conference Presentations
1. Wu ZJ, Ren Q, Simom G, Parel J-M. Photo-thermal Modeling Biomechanics of Laser
Photo-thermal Keratoplasty (LPTK). Presented at ARVO Annual Meeting May 1993.
Sarasota, Florida.
Page 21 Zhongjun Jon Wu, Ph.D.
2. Menon S, Li W, Wu ZJ, Haubold A and Hwang NH. A Long Body Mechanical Heart
Valve for Improved Hydrodynamic Performance. Presented at BMES 1993 Annual Fall
Meeting, Memphis, October 21-24, 1993.
3. Wang SK, Wu ZJ, Wang Y and Hwang NH. Deceleration of Bileaflet MHV at Closing
and Transient Pressure Reduction. Presented at BMES 1993 Annual Fall Meeting,
Memphis, October 21-24, 1993.
4. Wu ZJ, Menon S and Hwang NH. Impact and Rebound of Mechanical Heart Valve
(MHV) Leaflets at Closing. Presented at BMES 1993 Annual Fall Meeting, Memphis,
October 21-24, 1993.
5. Wang Y, Wu ZJ and Hwang NH. Squeeze Flow Fields at the Closing of Mechanical
Heart Valves. Presented at Second World Congress of Biomechanics. Amsterdam, the
Netherlands, July 10-15, 1994.
6. Salat O, Wu ZJ, Glismann CC and Hwang NH. Adjustable Preload and Afterload for
Mock Flow Loop Testing of Prosthetic Heart Valves. Presented at Second World
Congress of Biomechanics. Amsterdam, the Netherlands, July 10-15, 1994.
7. Hwang NH, Wu ZJ and Fung KY. Mechanical Heart Valve Closing Velocity and
Cavitation Potential. Presented at the Second Sheffield Symposium of Heart Valve
Replacement. Sheffield, UK, October 1994.
8. Wu ZJ and Hwang NH. Mounting Orientations and The Closure Behavior of a
Monoleaflet Mechanical Heart Valve. Presented at 1994 BMES Annual Meeting, Tempe,
Arizona, October 14-16, 1994.
9. Wu ZJ, Wang SK and Hwang NH. Regurgitant Jet Profiles in Asynchronous Closure of
Bileaflet Mechanical Heart Valves. Presented at ASAIO 1995 Annual Meeting, Chicago,
May 4-6, 1995.
10. Wu ZJ, Gao BZ, Ritter C and Hwang NH. Effect of Housing Compliance on Mechanical
Heart Valve (MHV) Transient Pressure at Closing. P resented at 1995 BMES Annual
Meeting, Boston, October 6-8, 1995.
11. Wu ZJ, Gao BZ, Slonin JH and Hwang NH. Performance of Bileaflet Mechanical Heart
Valves at Low Cardiac Output,” Presented at ASAIO 1996 Annual Meeting, Washington,
DC, May 1996.
12. Wu ZJ, Slonin JH and Hwang NH. Transient Pressure Signals as A Means in Measuring
Mechanical Heart Valve Cavitation Potential. Presented at 1996 Fall BMES Annual
Meeting, State College, PA, October 2-4, 1996.
13. Antaki JF, Paden BE, Gurgreen GW, Groon NJ, Kameneva MV, Wu Z, Holmes JA and
Griffith BP. The ‘Streamliner’: a New Mixed Flow Blood Pump with Magnetic Bearings.
Presented at 5th Congress of the International Society for Rotary Blood Pumps. Marseille,
France, September 1997.
14. Antaki JF, Choi S, Thomas D, Amin D, Litwak P, Wu ZJ and Boston RJ. In Search of ...
Hemodynamic Control for Rotary Blood Pumps 2: Architecture, Algorithms, and
Setpoints. Presented at 5th Congress of the International Society for Rotary Blood Pumps.
Marseille, France, September 1997.
15. Wu ZJ and Hwang NH. Cavitation in Mechanical Heart Valves: A Squeeze Flow
Phenomenon. Presented at 1997 BMES Annual Meeting, San Diego, CA, October 1997.
16. Curtis AS, Wu ZJ, Antaki JF. Transparent Compliant Left ventricle for Flow
Visualization of Apical Cannulation. Presented at 1997 BMES Annual Meeting, San
Page 22 Zhongjun Jon Wu, Ph.D.
Diego, CA, October 1997.
17. Lardo AC, Webber SA, Wu ZJ, Friehs I, del Nido PJ, Cape EG. Effect of accessory
pulmonary blood flow in the bidirectional superior vena cava anastomosis: a quantitative
fluid dynamics study. Presented at the American Heart Association 70th Scientific
sessions. Orlando, FL. November 1997.
18. Curtis AS, Meyer RK, Wu ZJ, Burgreen GW and Antaki JF. Application of
Bioluminescent Plankton for Shear Stress Measurement within Circulatory Assist
Components. Presented at International Conference on Mechanics in Medicine and
Biology, Honolulu, Hawaii, March 1998.
19. Burgreen GW, Antaki JF, Wu ZJ, LeBlanc P, Butler KC, Kormos, RL. A computational
and experimental comparison of two outlet stators for the Nimbus LVAD. In: The 44th
Meeting of the American Society of Artificial Internal Organs. New York NY, April 23-
25, 1998.
20. Amin D, Antaki JF, Litwak P, Thomas D, Wu ZJ, Watach M, Butler KC. Introduction of
ventricular collapse by axial flow blood pump. IN: The 44th Meeting of the American
Society of Artificial Internal Organs. New York NY, April 23-25, 1998.
21. Wu ZJ, Antaki JF, Burgreen GW, Butler K, Thomas D, and Griffith BP. Fluid dynamic
characterization of operating conditions for continuous flow blood pumps. In: The 44th
Meeting of the American Society of Artificial Internal Organs. New York, NY, April 23-
25, 1998.
22. Antaki JF, Paden BE, Gurgreen GW, Kameneva MV, Wu ZJ, Holmes JA, Paden D,
Groom NJ, and Griffith BP. Development Progress of the Streamliner Mixed Flow Blood
Pump with Magnetic Bearings. Presented at 6th Congress of the International Society for
Rotary Blood Pumps. Utah, July 1998.
23. Antaki JF, Wu ZJ, Gurgreen GW, Sorensen EN, Holmes JA and Griffith BP. Fluid
Dynamic Phenomena within A magnetically Levitated Mixed Flow Blood Pump.
Presented at the Third World Congress of Biomechanics. Sapporo, Japan, August 1998.
24. Wu ZJ, Kameneva MV, Repko BM, Butler KC and Antaki JF. Relationship between
fluid dynamics and hemolysis of an axial flow blood pump. The 1998 BMES annual
meeting, Cleveland, OH, October 1998.
25. Lardo AC, Webber SA, Iyenagar A, Wu Z, Friehs I, del Nido PJ, Cape EG. Pulmonary
flow dynamics of the bidirectional superior cavopulmonary anastomisis with accessory
main and aortopulmonary flow sources. The American Heart Association 71st Scientific
sessions. November 1998, Dallas, TX.
26. Iyengar AK, Park SC, Wu ZJ, Neches WH. Hemodynamic considerations in the genesis
of coarctation of aorta: an in vitro study of fetal cardiac circulation. American Society of
Echocardiography: 10th Annual Scientific Sessions, Washington, DC, June 1999.
27. Wu ZJ, Antaki JF, Ewing B, Kameneva MV, Repko BM, Thomas DC, Butler KC.
Operating range for axial flow blood pump: relationship of fluid dynamics, efficiency, and
hemolysis. In: The 44th Meeting of the American Society of Artificial Internal Organs.
San Diego, CA, June 2-5, 1999.
28. Antaki JF, Wu J, Boston, Baloa L, Choi S, Litwak K, Litak P, L McCue, Thomas, D, Butler
KC. In continued search of … control for turbodynamic blood pumps. In: The 44th
Meeting of the American Society of Artificial Internal Organs. San Diego, CA, June 2-5,
1999.
Page 23 Zhongjun Jon Wu, Ph.D.
29. Antaki JF, Gurgreen GW, Wu ZJ, Borzelleca D, Kameneva MV, Holmes JA, Litwak P,
Litwak K, Watach M, Paden BE, Dragnes T, Groom NJ and Griffith BP. Development
Progress of the University of Pittsburgh Streamliner: a Mixed Flow Blood Pump with
Magnetic Bearings. Presented at In: The 46th Meeting of the American Society of
Artificial Internal Organs. New York, NY, June 28-July1, 2000.
30. Butler K, Thomas D. Taylor L, Petersen T, Poirier V, Parsaie F, Kormos R, Borovetz H,
Litwak P, Litwak K, Kameneva M, Wu J, Antaki J, Watach M. The Heartmate II Axial
flow LVAS: Journey towards Clinical Trial. In: The 46th Meeting of the American
Society of Artificial Internal Organs. New York, NY, June 28-July1, 2000.
31. Wu ZJ, Holmes JA, Griffith BP, Gartner MJ. Flow Dynamics of an Active Mixing
Pump-Oxygenator. The 47th Meeting of the American Society of Artificial Internal
Organs. New York, NY, June 28-July1, 2000.
32. Gottlieb R, Antaki J, Wu Z, Griffith BP. Visualization of wall shear stress in blood-
wetted artificial organs using new photochromic liquid crystal sensor. The 47th Meeting
of the American Society of Artificial Internal Organs. New York, NY, June 28-July1,
2000.
33. Antaki JF, Liu Y, and Wu ZJ. Cannula design can reduce regurgitant flow during VAD
stoppage: when a check valve is not a check valve. The 47th Meeting of the American
Society of Artificial Internal Organs. New York, NY, June 28-July1, 2000.
34. Snyder TA, Wu J, Antaki JF, Burgreen GW, Wagner WR. In vitro investigation of shear-
induced platelet activation in axial flow VADS. The 47th Meeting of the American
Society of Artificial Internal Organs. New York, NY, June 28-July1, 2000.
35. Kihara S, Litwak KN, Litwak P, Nichols L, Wu ZJ, Kormos L. Lower assist rate is
associated with pathology of renal cortex arteries with continuous flow left ventricular
assist in calves. Presentation at ASAIO Annual Meeting, New York, NY, June 13-15,
2002.
36. Litwak KN, Wu ZJ, Kihara S. Altered Aortic hemodynamics with Continuous VAD
Support. Presentation at ASAIO Annual Meeting, New York, NY, June 13-15, 2002.
37. Antaki JF, Boston JR, Simaan M, Wu ZJ. Current Strategies for Control of
Turbodynamic Blood Pumps. Presented at 2nd Joint Conference of the IEEE Engineering
in Medicine and Biology Society and the Biomedical Engineering Society, Houston, TX,
October 2002
38. Wu ZJ, Antaki JF, Litwak K, Kameneva MV, Borovetz HS, Kormos R. Ventricular
assist devices: current status and future perspective. World Congress for Chinese
Biomecial Engineers, Taipei, Taiwan, December 2002.
39. Wu ZJ, Marascalco P, Marhefka J, Kameneva MV. Increased Red Blood Cell
Deformation by Minute Concentrations of Blood Soluble Drag-Reducing Polymers
(DRPs). ASAIO-ISAO Joint Conference. Washington DC, June 19-21, 2003.
40. Litwak KN, Kihara S, Wu Z, Sinha A, Lohman D and Koenig S. Pulsatile and
continuous flow vad aortic hemodynamics: outflow graft location is the key. ASAIO-
ISAO Joint Conference. Washington DC, June 19-21, 2003.
41. Antaki JF, Ludlow JC, Miles SD, Wu J, Burgreen GW, Wu Z, Khanwilkar P, Long J.
Low-profile inlet for centrifugal pump. ASAIO-ISAO Joint Conference. Washington
DC, June 19-21, 2003.
Page 24 Zhongjun Jon Wu, Ph.D.
42. Marascalco PJ, Marhefka J, Wu Z, Kameneva M. Effect of drag reducing moplymer
(DRPs) on red blood cell (RBC) filterability. ASAIO-ISAO Joint Conference.
Washington DC, June 19-21, 2003.
43. Hildebrand D, Wu J, Mayer J, Sacks M. Development and Evaluation of a Novel
Pulsatile Flow Loop for Biologically Active Heart Valves. Society for Heart Valve
Disease 2nd Biennial Meeting, Paris, France, June 28 – July 1, 2003.
44. Wu ZJ, Zhao R, Fu A, Marascalco P, Antaki JF and Kameneva MV. Effect of Drag
Reducing Polymers On Microscale Flow Behavior Of Red Blood Cells. Second
International Interdisciplinary Conference on Cardiovascular Medicine and Science,
Bethesda, Maryland. July 23-25, 2003.
45. Wu ZJ, Zhao R, Kameneva MV and Antaki JF. Blood Cell Tracking Velocimetry for
Studying Flow-Induced Blood Damage Dynamics. Second International Interdisciplinary
Conference on Cardiovascular Medicine and Science, Bethesda, Maryland. July 23-25,
2003.
46. Wu ZJ, Marascalco PJ, Smith GC, Marhefka JN, and Kameneva MV. Effect of drag-
reducing polymers on red blood cells in microchannel flow. 75th Annual Meeting of the
Society of Rheology. Pittsburgh, PA, October, 2003.
47. ZJ Wu, WJ Federspiel. DPIV flow study of a pulsating artificial lung catheter. ASAIO
50th Anniversary Conference, Washington DC, June 17-19, 2004
48. Zhao R, Antaki JF, Wu ZJ, Kameneva MV, Bachman T. Investigation of microscale
blood flow behavior and shear-induced blood damage by cell tracking velocimetry.
ASAIO 50th Anniversary Conference, Washington DC, June 17-19, 2004
49. Dague C, Bourgue K, Loree H, Farrar D, Gurgreen G, Hampton E, Fleischli A, Gempp T,
Schoeb R, Wu ZJ, K Litwak K, Watach M, Tamez D, Gregoric ID, Clubb FJ, Frazier
OH. CFD and flow visualization analyses of critical gaps in a rotary pump, with in vivo
corroboration. ASAIO 50th Annual meeting, Washington DC, June 17-19, 2004.
50. Zhao R, Antaki JF, Wu ZJ, Diao C, Kameneva MV. Red Blood Cell Response to Supra-
physiologic Shear Stress in Micro-channels with Different Geometries. Presented at 2004
BMES Annual Meeting, Philadelphia, PA, Oct 13 ~16, 2004
51. Wu ZJ, Zhang JT, Nolan TD, Chambers S, and Griffith BP. Development of a Novel
Integrated Pump Oxygenator. Presented at the American Society for Artificial and
Internal Organs 51st Annual Conference, Washington DC, June 9-11, 2005.
52. Zhang J, Nolan TDC, Griffith BP, and Wu ZJ. Prediction of Oxygenation, Hemolysis
and Thrombosis in Blood Membrane Oxygenators Using Computational Fluid Dynamics.
Presented at the American Society for Artificial and Internal Organs 51st Annual
Conference, Washington DC, June 9-11, 2005.
53. Prastein DJ, Kilic A, Ayala T, Wu ZJ, and Griffith BP. Myocardial Strain Map of
Remodeling. Presented at the American Society for Artificial and Internal Organs 51st
Annual Conference, Washington DC, June 9-11, 2005.
54. Kilic A., Prastein D.J., Schwartzbauer G., Wu ZJ, and B.P. Griffith. Regional SERCA2a
Protein Expression in the Post-MI Model of Heart Failure. Presented at the American
Society for Artificial Internal Organs 51st Annual Conference, Washington DC, June 9-
11, 2005
55. Nash JR, Kilic A, Prastein D, Li T, Nolan TDC, Schwartzbauer G, Griffith BP, and Wu
ZJ. Left Ventricular Regional Strains and Protein Expression Predict Remodeling Post
Page 25 Zhongjun Jon Wu, Ph.D.
Myocardial Infarction. Presented at the Biomedical Engineering Society Annual Fall
Meeting, September 28-October 1, 2005
56. Zhang J, Griffith BP, and Wu ZJ. CFD Based Multi-objective Analysis and
Optimization of Blood Oxygenating Devices. Presented at the Biomedical Engineering
Society Annual Fall Meeting, September 28-October 1, 2005
57. Kilic A, Li T, Nash J, Prastein D, Schwartzbauer G, Nolan T, Wu Z, Griffith B. Strain
Related Regional Alteration of Sarcoplasmic Reticulum ATPase in Heart Failure. 3rd
International Congress, The Failing Heart Under Stress, Amsterdam, Netherlands,
November 2005.
58. Li T, Kilic A, Nash J, Prastein D, Schwartzbauer G, Nolan T, Wu Z, Griffith B. Strain
Related Alterations of the Phosphoinositide 3-Kinase / Akt / BAD Survival Pathway.
JACC Supp 2006 47 (Issue 4, Supp. 1): 76A.
59. Kilic A, Li T, Nash JR, Prastein DJ, Schwartzbauer G, Nolan TDC, Wu Z, Griffith BP.
Strain Related Regional Alterations of Calcium Handling Proteins in Heart Failure.
American Association for Thoracic Surgery. 86th Annual Meeting, Philadelphia, PA,
April 2006.
60. Kilic A, Nash J, Li T, Prastein D, Schwartzbauer G, Nolan T, Wu Z, Griffith B.
Mechanical Unloading of the Failing Heart Restores Strain Related Calcium Handling
Protein Expression. J Heart Lung Trans Supp 2006 25 (Issue 2, Supp. 1): S103.
61. Kilic A, Nolan TDC, Li T, Yankey GK, Prastein DJ, Jarvik R, Wu Z, Griffith BP.
Chronic In-Vivo Hemodynamic Study of the Pediatric Jarvik 2000 Heart. 52nd Annual
ASAIO Conference, Chicago, IL, June 2006.
62. Wu ZJ, Kilic A, Nolan TDC, Li T, Yankey GK, Jarvik R, Griffith BP. Compensatory
Hemodynamic and Biologic Responses to Pediatric Circulatory Support in Lambs. 52nd
Annual ASAIO Conference, Chicago, IL, June 2006.
63. Wu ZJ, Zhang J, Nolan TDC, Zhang T, Griffith BP. Computational and experimental
evaluation of an integrated blood pump oxygenator. Presentation at 5th World Congress of
Biomechanics, Munich, Germany, July 28 ~ August 4, 2006.
64. Zhang J, Zhang T, Nolan TDC, Griffith BP, Wu ZJ. Toward a Multi-Objective Model for
Artificial Lung Devices. Presentation at 5th World Congress of Biomechanics, Munich,
Germany, July 28 ~ August 4, 2006.
65. Kilic A, Yankey GK, Nolan TDC, Li T, Cheng G, Wu Z, Griffith BP. Regional Systolic
and Remodeling Strain Differences during Cardiac Remodeling. American College of
Surgeons 92nd Annual Clinical Congress, Chicago, IL., October, 2006
66. Wu ZJ, Kilic A, Zhang J, Burgreen G, Cheng G, Yankey GK, Li T, Jarvi RK, Griffith
BP. Progress and Initial In-Vivo Experience of the Pediatric Jarvik 2000 Hearts. ISHLT,
2007, San Francisco.
67. Yankey GK, Li T, Kilic A, Moainie S, Weidenhamer N, Nolan T, Cheng G, Prastein D,
Schwartzbauer G, Wu ZJ, Griffith BP. Regional Remodeling Strain and Its Association
with Myocardial Apoptosis Post-Myocardial Infarction in Ovine Model. 87th Annual
American Association for Thoracic Surgery Meeting, Washington, D.C.; May 2007
68. Yankey GK, Nolan T, Wu ZJ, Griffith BP, Gammie JS. Epicardial Cryoablation Reliably
Produces Transmural Lesions on the Beating Heart. ISMICS, Rome, Italy, June, 2007
69. Zhang J, Koert A, Zhang T, Gellman B, Dasse KA, Gilbert RJ, Griffith BP, Wu ZJ.
Computational Fluid Dynamics Analysis of an Integrated Maglev Pump-Oxygenator
Page 26 Zhongjun Jon Wu, Ph.D.
(IMPO). Presented at 53rd ASAIO Annual Conference, June 7-9, 2007 - Chicago, IL
70. Wu ZJ, Gellman B, Zhang J, Koert A, Zhang T, Dasse KA, Griffith BP. An Integrated
Maglev Pump-Oxygenator (IMPO). Presented at 53rd ASAIO Annual Conference, June
7-9, 2007 - Chicago, IL
71. Wu ZJ, Li T, Yankey GK, Kilic A, Cheng G, Savai K, Griffith BP. LV regional strains
and activation of molecular survival and apoptotic pathways post myocardial infarction.
Presentation at BMES 2007 Annual Fall Meeting, Los Angeles, CA, September 26-29,
2007.
72. Zhang T, Zhang J, Nolan TDC, Griffith BP, Wu ZJ. Benchmark Study of Oxygen
Transfer in Microporous Hollow Fiber Membrane (HFM) Bundles. Presentation at BMES
2007 Annual Fall Meeting, Los Angeles, CA, September 26-29, 2007.
73. Yankey GK, Li T, Kilic A, Savai K, Cheng G, Satpute A, Wu ZJ, Griffith BP. Strain
Related Changes in Regional Myocardial Cyclin-Dependent Kinase (Cdk) Inhibitor
Protein, p21 Post-Myocardial Infarction in Ovine Model. American College of Surgeons,
Meeting, New Orleans, LA, October 2007
74. Cheng G, Farnan R, Jarvik RK, Griffith BP, Wu ZJ. In Vivo Experience with Different
Types of Assist Devices for Heart Unloading. Presented at the 54th ASAIO Annual
Conference, San Francisco, CA. June 19-21, 2008.
75. Zhang T, Griffith BP, Wu ZJ. Characterization of hollow fiber membrane bundles in
benchmrak test. Presented at the 54th ASAIO Annual Conference, San Francisco, CA.
June 19-21, 2008.
76. Taskin ME, Zhang T, Gellman B, DasseKA, Griffith BP, and Wu ZJ. Computational
flow and blood damage modeling of the ultramag™ blood pump. Presented at the 54th
ASAIO Annual Conference, San Francisco, CA. June 19-21, 2008.
77. Zhang T, Wu C, Snyder T, Jarvik R, Griffith BP, Wu ZJ. Study of blood damage using a
newly developed blood shearing device. Presented at the 54th ASAIO Annual
Conference, San Francisco, CA, June 19-21, 2008.
78. Savai K, Wu C, Farnan R, Cheng G, Morley D, Griffith BP, and Wu ZJ. The Impact of
Partial Circulatory Support on the Strain Distribution on the Post-Infarction Left
Ventricular Wall. Presented at the 54th ASAIO Annual Conference, San Francisco, CA,
June 19-21, 2008.
79. Gao Y, Savai K, Li T, Wu C, Bond M, Wu ZJ, Griffith BP. Expression of Akt/Pim-1
Survival Proteins in Myocardial Remodeling. Basic Cardiovascular Sciences Conference
2008 - Heart Failure: Molecular Mechanisms and Therapeutic Targets. Keystone, CO, Jul
28-31, 2008.
80. Li T, Savai K, Wu C, Yankey GK, Cheng G, DeFilippi C, Bond M, Wu ZJ, Griffith BP.
Strain Activation of Calcineurin-Mediated Mitochondria Apoptotic Pathway after
Myocardial Infarction in Ovine Model. Basic Cardiovascular Sciences Conference 2008 -
Heart Failure: Molecular Mechanisms and Therapeutic Targets. Keystone, CO, Jul 28-31,
2008
81. Wu ZJ, Wilson A, Wu C, Veirs M, Chang WB, Savai K, Macvittie T, Griffith BP.
Transplantation of Mesenchymal Stem Cells Improves Myocardial Infarct Border Zone
Contractility. BMES Annual Fall Meeting, St. Louis, MO. October 2-4, 2008.
82. Taskin ME, Zhang T, Griffith BP, Wu ZJ, "A Combined CFD-based hemolysis
Prediction Approach for Biomedical Devices", BMES Annual Fall Meeting, St. Louis,
Page 27 Zhongjun Jon Wu, Ph.D.
MO. October 2-4, 2008.
83. Taskin ME, Zhang T, Griffith BP, Wu ZJ. Micro-Scale Modeling of Flow through
Hollow Fiber Membrane. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30,
2009.
84. Jarvik R, Wu ZJ, Griffith BP. Cone Bearings Enable Sub-Miniature Permanent Blood
Pumps. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30, 2009.
85. Zhang T, Taskin T, Wong T, Biancucci B, Wu ZJ, Griffith BP. Development of a
Wearable Pump-Lung. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30,
2009.
86. Fraser KH, Mihelc K, Gellman B, Dasse K, Griffith BP, Wu ZJ. CFD Analysis of
Thrombosis Potential in LVAD Drainage Cannulation. The 55th ASAIO Annual
Conference, Dallas, TX, May 28-30, 2009.
87. Gibber M, Chang WB, Hu J, Savai K, Jarvik R, Wu ZJ, Griffith BP. Pediatric Jarvik
2000 Heart Experience Update. The 55th ASAIO Annual Conference, Dallas, TX, May
28-30, 2009.
88. Wu C, Chang WB, Gibber M, Wu ZJ, Griffith BP. Acute Left Ventricular Unloading by
the Impella VAD. The 55th ASAIO Annual Conference, Dallas, TX, May 28-30, 2009.
89. Zhang T, TaskinM, Gellman B, Dasse K, Griffith BP, Wu ZJ. Link of Fluid Dynamic
Variables to Hemolysis in Blood Pumps. The 55th ASAIO Annual Conference, Dallas,
TX, May 28-30, 2009.
90. Jarvik R, Wu Z, Sherman C, Kavala L, and Griffith B. Summary at Completion of the
Jarvik 2000 NIH Pediatric Development Program. The Fifth International Conference on
Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary
Perfusion, Dallas, TX, May 28-30, 2009.
91. Farnan GG, Marsille O, Kerkhoffs W, Farnan RC, Wu C, Wu ZJ, Griffith BP. Pediatric
Application of the CircuLite Synergy Micro-Pump Technology. The Fifth International
Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric
Cardiopulmonary Perfusion, Dallas, TX, May 28-30, 2009.
92. Taskin ME, T Zhang, BP Griffith, and Wu ZJ. Computational and Experimental
Evaluation of an Artifical Pump-Lung Device. FDA / NHLBI / NSF Workshop on
Computer Methods for Cardiovascular Devices, June 1-2, 2009, Bethesda, Maryland.
93. Fraser KH, Taskin ME, Zhang T, Griffith BP, and Wu ZJ. The Influence of Taylor
Vortices in Centrifugal Ventricular Assist Devices on Blood Damage Potential.
FDA/NHLBI/NSF Workshop on Computer Methods for Cardiovascular Devices, June 1-
2, 2009, Bethesda, Maryland.
94. Wu ZJ, Gellman B, Zhang T, Mihelc K, Gibber M, Chang WB, Taskin M, Garcia J,
Dasse K, Griffith BP. Chronic In-vivo Performance of Pediatric Pump-Lung (PediPL) for
Cardiopulmonary/Circulatory Support. 2009 Biomedical Engineering Society Annual Fall
Meeting, Pittsburgh, October 7-10, 2009.
95. Wu ZJ, Zhang T, Taskin ME, Bianchi G, Wong P, Biancucci B, Griffith BP. An
Ultracompact Integrated Magnetically Levitated Pump-Lung for
Cardiac/Cardiopulmonary Support. 17th Congress of the International Society of Rotary
Blood Pumps (ISRBP). October 1 to 3, 2009, Singapore.
96. Fraser KH, Zhang T, Taskin ME, Chen C, Griffith BP, Wu ZJ. Design of a New Mag-
Lev Hemolyzer using CFD. The 56th ASAIO Annual Conference, Baltimore, MD, May
Page 28 Zhongjun Jon Wu, Ph.D.
27-29, 2010
97. Taskin ME, Zhang T, Gellman B, Dasse KA, Griffith BP, and Wu ZJ. Computational
evaluation of the pediatric scaled pump-lung (PediPL) device. The 56th ASAIO Annual
Conference, Baltimore, MD, May 27-29, 2010.
98. Engel E, Wei X, Bianchi G, Son HS, Griffith BP, Wu ZJ. Impella LVAD Effectively
Decreases Strains in Left Ventricle after Myocardial Infarction. The 56th ASAIO Annual
Conference, Baltimore, MD, May 27-29, 2010.
99. Bianchi G, Wei X, Li T, Engel E, Son HS, Wu ZJ, Griffith BP. Early unloading of
infarcted hearts prevents cardiac remodeling and preserves calcium homeostasis. The
56th ASAIO Annual Conference, Baltimore, MD, May 27-29, 2010.
100. Zhang T, Bianchi G, Gellman B, Dasse K, Garcia J, Wu ZJ, Griffith BP. 30 Day In-Vivo
Performance of an Integrated Pediatric Pump-Lung for Cardiac/Cardiopulmonary
Support. The 56th ASAIO Annual Conference, Baltimore, MD, May 27-29, 2010.
101. Zhou K, Hu J, Griffith BP, Wu ZJ. Evaluation of Platelet Activation in Ovines Implanted
with Integrated Pump-Lung Using Soluble P-Selectin. The 56th ASAIO Annual
Conference, Baltimore, MD, May 27-29, 2010.
102. Kon ZN, Tendukular A, Wu ZJ, Iacono A, McCormick B, Griffith BP, Garcia JP. Extra
Corporeal Membrane Oxygenation via cannulation of the internal jugular vein with a
dual-lumen Single Catheter System: A novel Approach for treatment of End-Stage Lung
Disease, 90th Annual American Association for Thoracic Surgery Meeting, Toronto, ON,
Canada; May 2010
103. Taskin ME, Zhang T, Fraser KH, Griffith BP, and Wu ZJ. Evaluation of Power-Law
Hemolysis Prediction Models. FDA/NHLBI/NSF Workshop on Computer Methods for
Cardiovascular Devices, June 10-11, 2010, Bethesda, Maryland.
104. Fraser KH, Taskin ME, Zhang T, Griffith BP, Wu ZJ. Comparison of Shear Stresses and
Residence Times in Different Ventricular Assist Devices. FDA/NHLBI/NSF Workshop
on Computer Methods for Cardiovascular Devices, June 10-11, 2010, Bethesda,
Maryland.
105. Griffith BP, Drummond A, Farnan R, Wu Z, Zhang T, Budris J, and Farnan G.
Feasibility of CircuLite’s Circulatory Support System in Children. The Sixth International
Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric
Cardiopulmonary Perfusion, Boston, May, 2010.
106. Wei X, Li T, Williams K, Bianchi G, Son HS, Li S, Wu ZJ, Griffith BP. Unloading with
left ventricular assist devices protects heart function by normalizing alterations of calcium
handling proteins after myocardium infarction. Presentation at AHA Scientific Sessions
2010, Chicago, IL, Nov. 13-17, 2010.
107. Wu ZJ, Gellman B, Zhang T, Dasse K, Garcia JP and Griffith BP. An Integrated
Pediatric Pump-Lung for Cardiac/Cardiopulmonary Support. ISHLT 31st Annual Meeting
and Scientific Sessions, April 13-16, 2011 San Diego, CA, USA.
108. Fraser K, Zhang T, Sorensen E, Hu J, Williams K, Feller E, Garcia J, Griffith B, Wu ZJ.
Mechanical Blood Damage in an Axial VAD compared to a Centrifugal VAD. ISHLT
31st Annual Meeting and Scientific Sessions, April 13-16, 2011 San Diego, CA, USA.
109. Wei X, Son H, Sanchez PG, Zhang P, Wu ZJ, Jarvik R, Griffith BP. Acute
Hemodynamic Evaluation of the Infant Jarvik Heart in a Piglet Animal Model.
Presentation at the 57th ASAIO Annual Conference, Washington DC, June 10 -12, 2011.
Page 29 Zhongjun Jon Wu, Ph.D.
110. Garimella N, Zhang T, Griffith BP, Wu ZJ. Prior Evaluation of Heparinized Hollow
Fiber Membrane Sample Surfaces. Presentation at the 57th ASAIO Annual Conference,
Washington DC, June 10 -12, 2011.
111. Fraser KH, Zhang T, Griffith BP, Wu ZJ. Larger Shear Stresses In Axial VADs Account
for Their Increased Hemolysis Risk Compared With Centrifugal VADs. Presentation at
the 57th ASAIO Annual Conference, Washington DC, June 10 -12, 2011.
112. Wu ZJ, Gellman BN, Zhang T, Wei X, Son H, Sanchez P, Vafiades D, Dasse K and
Griffith BP. Pre-Clinical Program of the Integrated Pediatric Pump-Lung (PediPL) for
Kids, Infants and Neonates. Presentation at the 57th ASAIO Annual Conference,
Washington DC, June 10 -12, 2011.
113. Zhang T, Fang HB, Jarvik J, Griffith BP, Wu ZJ. Study of Shear-induced Blood Damage
in Different Species. Presentation at the 57th ASAIO Annual Conference, Washington
DC, June 10 -12, 2011.
114. Zhou K, Niu S, Griffith BP, Wu ZJ. High Shear-short exposure time induced platelets
activation in different species. Presentation at the 57th ASAIO Annual Conference,
Washington DC, June 10 -12, 2011.
115. Hu J, Sorensen E, Feller E, Griffith BP, Wu ZJ. Evaluation of Contributing Factors to
Nonsurgical Bleeding in Continuous-flow Left Ventricular Assist Device (CF-LVAD)
Recipients. Presentation at the 57th ASAIO Annual Conference, Washington DC, June 10
-12, 2011.
116. Wei X, Li T, Williams K, Bianchi G, Son HS; Li S, DeFilippi C, Wu ZJ, Griffith BP.
Early short-term unloading with left ventricular assist device reduces regional
hypertrophy after myocardium infarction via multiple pathways. American Heart
Association (AHA) Scientific Session 2011, Orlando, Florida.
117. Wei X, Li T, Williams K, Bianchi G, Son HS; Li S, DeFilippi C, Wu ZJ, Griffith BP.
Short-term Mechanical Unloading by left ventricular assist device reduces infarct size and
prevents adverse remodeling after MI. The American College of Cardiology’s (ACC's)
61st Annual Scientific Session 2012, Chicago, Illinois.
118. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. Mechanical circulatory support to a
failing Fontan circulation in a piglet animal model. Presentation at American Society of
Artificial Internal Organs (ASAIO) 58th Annual Conference, San Francisco, California,|
June 13-16, 2012.
119. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. The physiological effects of the artificial
pump-lung device in a ovine animal model. American Society of Artificial Internal
Organs (ASAIO) 58th Annual Conference, San Francisco, California, June 13-16, 2012.
120. Wei X, Li T, Son HS; Li S, Wu ZJ, Griffith BP. The animal model for evaluation of the
pediatric VAD. Presentation at American Society of Artificial Internal Organs (ASAIO)
58th Annual Conference, San Francisco, California,| June 13-16, 2012.
121. Fraser KH, Taskin ME, Zhang T, Griffith BP and Wu ZJ. Flow weighted residence time:
a useful indicator of hemolysis. Presentation at American Society of Artificial Internal
Organs (ASAIO) 58th Annual Conference, San Francisco, California, June 13-16, 2012.
122. Garimella N, Gellman B, Griffith BP, Wu ZJ. In-Vivo Hemocompatibility of
Heparinized Hollow Fiber Membranes of the Pediatric Pump-Lung (PediPL) Device.
Presentation at American Society of Artificial Internal Organs (ASAIO) 58th Annual
Conference, San Francisco, California, June 13-16, 2012.
Page 30 Zhongjun Jon Wu, Ph.D.
123. Niu S, Zhang T, WIllaims K, Griffith BP, Wu ZJ. Shear Induced Platelet Activation And
Signal Transduction. Presentation at American Society of Artificial Internal Organs
(ASAIO) 58th Annual Conference, San Francisco, California, June 13-16, 2012.
124. Hu J, Watkins AC, Niu N, Romar L, Hiivala NJ, Fraser K, Feller ED, Griffith BP, Wu
ZJ. Mitochondrial Damage: Potential Mechanism of Platelet Dysfunction Leading to
Nonsurgical Bleeding Complications in CF-LVAD Patients. Presentation at American
Society of Artificial Internal Organs (ASAIO) 58th Annual Conference, San Francisco,
California, June 13-16, 2012.
125. Zhang J, Zhang P, Fraser KH, Griffith BP, Wu ZJ. Comparison of Fluid Dynamic
Numerical Models for a Clinical Ventricular Assist Device and Experimental Validation.
Presentation at American Society of Artificial Internal Organs (ASAIO) 58th Annual
Conference, San Francisco, California, June 13-16, 2012.
126. Grimella N, Griffith BP, Wu ZJ. Comparative Biocompatibility Assessment of Coatings
Applied On hollow Fiber Membranes of Blood Oxygenators. Presentation at American
Society of Artificial Internal Organs (ASAIO) 59th Annual Conference, Chicago, IL,
California, June 12-15, 2013.
127. Zhang J, Fraser KH, Teal J, Jarvik R, Griffith BP, Wu ZJ. Comparison of Two Impellers
for the Jarvik Infant Pump: a Computational Fluid Dynamics (CFD) Study. Presentation
at American Society of Artificial Internal Organs (ASAIO) 59th Annual Conference,
Chicago, IL, California, June 12-15, 2013.
128. Mondal NK, Sorensen EN, Hiivala N, Feller ED, Griffith BP, Wu ZJ. Higher expression
of AGNOR and NOR Associated Proteins in Blood Leukocytes of Heart Failure Patients
Supported by Continuous Flow Left Ventricular Assist Devices (LVADs). Presentation at
American Society of Artificial Internal Organs (ASAIO) 59th Annual Conference,
Chicago, IL, California, June 12-15, 2013.
129. Watkins AC, Wei X, Sanchez PG, Liu Y, Bittle GJ, Li T, Narain A, Repetto M, Faria E,
Li S, Jarvik R, Wu ZJ, Griffith BP. Evaluation of the Infant Jarvik Ventricular Assist
Device in a Chronic Juvenile Sheep Model. Presentation at the International Society for
Heart and Lung Transplantation 33rd Annual Meeting and Scientific Sessions, Montreal,
Canada, April 24-27, 2013.
130. Mondal NK, Sorensen EN, Hiivala, Feller ED, Griffith BP, Wu ZJ. Oxidative Stress
Induced DNA Damage and Repair in Heart Failure Patients Supported by Continuous
Flow Ventricular Assist Devices. Presentation at the International Society for Heart and
Lung Transplantation 33rd Annual Meeting and Scientific Sessions, Montreal, Canada,
April 24-27, 2013.
131. Pasrija C, Sanchez PG, Wu ZJ, Griffith BP. Developing a Novel Large Animal Model of
Trauma-Induced Systemic Inflammatory Response Syndrome. Presentation at Clinical
Congress 2013 of the American College of Surgeons. Washington DC, Ocb. 6-10,2013.
132. Mondal NK, Sorensen EK, Hiivala N, Feller ED, Pham S, Griffith BP and Wu ZJ.
Intraplatelet reactive oxygen species, mitochondrial damage and platelet apoptosis
augment non-surgical bleeding in heart failure patients supported by continuous-flow left
ventricular assist device (CF-LVADs). Presentation at the International Society for Heart
and Lung Transplantation (ISHLT) 34th Annual Meeting and Scientific Sessions, April
10-13, 2014, San Diego, CA.
Page 31 Zhongjun Jon Wu, Ph.D.
133. Liu Y, Sanchez PG, Narain A, Wei X, Watkins AC, Wu ZJ, Griffith BP. Thirty-Day
Cardiopulmonary Support with a Novel Portable Pediatric Artificial Pump-Lung.
Presentation at the International Society for Heart and Lung Transplantation (ISHLT)
34th Annual Meeting and Scientific Sessions, April 10-13, 2014, San Diego, CA.
134. Mondal NK, Sorensen EN, Feller ED, Rajagopal K, Pham SM, Griffith BP and Wu ZJ.
Comparison of Intraplatelet Reactive Oxygen Species, Mitochondrial Damage and
Platelet Apoptosis after HeartMate II, Jarvik 2000 and HeartWare Left Ventricular Assist
Device implantation. Presentation at American Society of Artificial Internal Organs
(ASAIO) 60th Annual Conference, Washington DC, June 18-21, 2014.
135. Niu S, Griffith BP, Wu ZJ. In-Vitro Shear Stress-Induced platelet activation: Differences
between Species: Human, Ovine, and Porcine. Presentation at American Society of
Artificial Internal Organs (ASAIO) 60th Annual Conference, Washington DC, June 18-
21, 2014.
136. Zhang J, Ding J, Griffith BP, Wu ZJ. Computational Study of Blood Damage Potential in
Three Types of Hollow Fiber Membrane Bundles. Presentation at American Society of
Artificial Internal Organs (ASAIO) 60th Annual Conference, Washington DC, June 18-
21, 2014.
137. Liu Y, Sanchez PG, Watkins AC, Li T, Griffith BP, Wu ZJ. An Ovine Animal Model for
Long Term Evaluation of Artificial Pump Lungs. Presentation at American Society of
Artificial Internal Organs (ASAIO) 60th Annual Conference, Washington DC, June 18-
21, 2014.
138. Liu Y, Sanchez PG, Watkins AC, Niu S, Teal J, Jarvik R, Wu ZJ, Griffith BP. Sixty-Day
In Vivo Performance of Infant Jarvik 2000 Heart In a Juvenile Sheep Model. Presentation
at American Society of Artificial Internal Organs (ASAIO) 60th Annual Conference,
Washington DC, June 18-21, 2014.
139. Scotti C, Debus K, Horner M, Goodin M, Hariharan P, Chow R, Zhang J, and Wu ZJ.
Fluids Perspective on the CAM as Applied to Centrifugal and Axial Blood Pumps.
Presentation at ASME 2014 Verification and Validation Symposium. Las Vegas, NV.
May 7, 2014.
Invited Lectures and Talks
1. Department of Mechanical Engineering, University of Pittsburgh. “Laser-based flow
visualization in medical devices.” March 15, 2002.
2. Keynote Speaker, World Congress for Chinese Biomecial Engineers, Taipei, Taiwan.
“Ventricular assist devices: current status and future perspective”. December 4, 2002.
3. Keynote Speaker, the 2nd International Joint Congress of the International Federation for
Artificial Organs (IFAO) and Japanese Society for Artificial Organs (JSAO). Osaka,
Japan. “Progress and In-Vivo Experience of the Pediatric Jarvik 2000 Hearts”. October
29, 2007.
4. Hunter Distinguished Lecture, Department of Bioengineering, Clemson University.
“Development of an Integrated Artificial Pump-Lung: From Concept to In-vivo
Evaluation”. November 9, 2007.
Page 32 Zhongjun Jon Wu, Ph.D.
5. ChBE Department Seminar, Illinois Institute of Technology. “Fluid Dynamics and
Related Phenomena in Cardiovascular Artificial Organs”. December 5, 2007.
6. Distinguished Lecture, Korea University Artificial Organ Center, Seoul, Korea.
“Development of an Ambulatory artificial pump-lung for respiratory failure and blood
pumps for reversing cardiac remodeling post myocardial infarction”. June 22, 2008.–
7. Graduate Seminar, Fischell Department of Bioengineering, University of Maryland
College Park. "Development of Artificial Pump-Lung Technology: From Concept to
Bedside". March 11, 2011.
8. Graduate Seminar, Department of Chemical and Molecular Engineering, University of
Maryland College Park. "Use of Computational Fluid Dynamics in Development of
Cardiovascular Medical Devices: From Concept to Clinical Practice". February 7, 2012.
9. Invited Speaker at ASAIO 58th Annual Conference, San Francisco, California | June 13-
16, 2012, Bioengineering Track 3: Blood Damage and Thrombosis Modeling. "Blood
Damage." June 15, 2012.
10. Invited Speaker at ASAIO 58th Annual Conference, San Francisco, California | June 13-
16, 2012, Pulmonary Track 3: New and Novel Artificial Lung Technologies. "Design and
Optimization of an Integrated Artificial Pump-Lung for Respiratory Support." June 16,
2012.
11. Featured Faculty Speaker at China Heart Congress (CHC) 2012, Beijing, August 9 to 12,
2012. "Circulatory Assist Devices for Heart Failure: from Concepts to Clinical Use."
August 9, 2012.
12. Invited Research Seminar, “Recent development in ventricular assist devices and
extracorporeal membrane oxygenation (ECMO)”. Soochow University, Cardiovascular
Research Institute. April 18, 2013.
13. Invited Speaker at the 7th Five-Continent International Symposium on Cardiovascular
Diseases. Beijing, April 19-21, 2013. “Recent Advances of Extracorporeal Membrane
Oxygenation (ECMO).” April 21, 2013.
14. Invited Speaker at ASAIO 59th Annual Conference, Chicago, Illinois, June 12-16, 2013,
Pulmonary Track 3 Evolving Technologies in Artificial Lung: “Wearable Artificial
Pump-Lung for Ambulatory Respiratory Support.” May 14, 2013.
15. Distinguished Visitor Lecture, University of Louisville, Division of Cardiothoracic
Surgery and Cardiovascular Innovation Institute. “Use of Computational Fluid Dynamics
in Development of Cardiovascular/Cardiopulmonary Medical Devices: From Concept to
Clinical Practice”. June 25, 2013.
16. Invited Speaker at US FDA Public Workshop - Methods for Thrombogenicity Testing.
“Thrombogenicity of Mechanical Circulatory Support Devices: Experience and
Challenges from Design to Clinical Use”, FDA White Oak Campus, Silver Spring, MD,
20993. April 14, 2014.
Page 33 Zhongjun Jon Wu, Ph.D.
17. Invited Speaker at 7th World Congress of Biomechanics. “A Pediatric Pump-Lung
(PediPL) for Kids, Infants, and Neonates: Challenges and Progress”. Boston, MA 02215.
July 6-11,2014
18. Invited Speaker at 7th World Congress of Biomechanics. “Computational fluid dynamic
analysis and In-vivo hemodynamics of Jarvik 2000 Infant VAD”. Boston, MA 02215.
July 6-11,2014
19. Invited Speaker at 2014 BMES Annual Meeting - Biomedical Engineering Society.
“CFD-Based Multi-Objective Modeling of Artificial Lung Devices” October 22-25, 2014
in San Antonio, Texas.
20. Graduate Seminar, Department of Mechanical Engineering, University of Maryland
Baltimore County. "Development of Cardiovascular Medical Devices: From Concept to
Clinical Practice". Sept. 26, 2014